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Anal dysplasia and anal cancer. English version
HIV InSite Knowledge Base
Background: Human papillomavirus HPV is well known as the major etiological agent for ano-genital cancer. In contrast to cervical cancer, anal cancer is uncommon, but is increasing steadily in the community over the last few decades. There is also less evidence reporting on the putative precursor lesion to anal cancer AIN - anal intraepithelial neoplasia , when compared to cervical cancer and CIN cervical intraepithelial neoplasia. This review summarises the available biological and epidemiological evidence for HPV in the anal site and the pathogenesis of AIN and anal cancer amongst traditionally non-high risk groups. Summary: There is strong evidence to conclude that high-grade AIN is a precursor to anal cancer, and some data on the progression of AIN to invasive cancer.
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Screening for Anal Dysplasia and Cancer in Patients with HIV
I read somewere that HPV can be spread through contact with any skin including hands, so I was wondering if it's possible to contract HPV through masturbation, or mutual masturbation with a partner? There are many types of HPV. Some types of HPV-genital warts are transmitted by skin-to-skin contact.
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Physician's assessment of ablation as optimal complete ablation versus sub-optimal incomplete ablation in the affected area in the anal canal. Subject tolerability of the RFA procedure as measured by severity.